It is specifically designed for it and the new ATI models. I think you will find that on the box it will say Supports Nvidia SLI and ATI Crossfire. Out of the box it has the most advanced GFX engine to date and actually requires an Nvidia 7x00 or Radeon x1x00 to enjoy full details at native TFT resolutions. If you have anything below a 16 pipeline card, you will struggle with details.