Hey Guys,

I've been on a PC for ~18 years now - and my hands are now started hurting (RSI, Google it up) -
My suggestions to you:

Keyboard: I haven't found a comfortable, non damaging keyboard yet - I am going to try the logitech LX series and the new Comfort 4000 MS Keyboard

Mouse: Whatever gaming mouse you get, try and get this one: http://www.evoluent.com/vmouse2.html too, for everything you do (I've been using it for a month or two, and you get used to it, haven't given it a go for gaming yet though) - It really relieves the mouse hand...

my 2 cents