I experienced the same when the demo version crashed. Better choose "no", then the game will try to start up normally again.
If that doesn't work, then run save mode (thus choose "yes" when this message appears). Then end the game when you are in the main menu. Then start the game again.
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Intel Core 2 Duo E8400 @ 3 Ghz - 2 GB Crucial Ballistix pc-8500 - Sapphire Radeon HD 4850 - 320 GB Seagate Barracuda (7200 rpm, 16 MB)
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